Article
Macrophages and dendritic cells: the usual suspects in atherogenesis.
Current drug targets - 1 Jan 2015
Kassiteridi Christina, Monaco Claudia
Abstract excerpt
Atherosclerosis, the major risk factor for cardiovascular disease (CVD) and the leading cause of death worldwide, is a multifactorial chronic inflammatory disease, which, clinically manifests from early lipid-rich lesions to plaque rupture and/or thrombosis in the arterial wall. The myeloid cell compartment, including macrophages and dendritic cells (DCs), is long known to contribute to the initiation and...
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