Article
Derivatives of biarylalkyl carboxylic acid induce pleiotropic phenotypes in adult Schistosoma mansoni in vitro.
Parasitology research - 1 Oct 2016
Blohm Ariane S, Mäder Patrick, Quack Thomas, Lu Zhigang, Hahnel Steffen, Schlitzer Martin, Grevelding Christoph G
Abstract excerpt
Schistosomes and other parasitic platyhelminths cause infectious diseases of worldwide significance for humans and animals. Despite their medical and economic importance, vaccines are not available and the number of drugs is alarmingly limited. For most platyhelminths including schistosomes, Praziquantel (PZQ) is the commonly used drug. With respect to its regular application in mass treatment programs, however,...
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