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Article

Schistosome ABC multidrug transporters: From pharmacology to physiology

26 Sept 2014

Abstract excerpt

Praziquantel (PZQ) is essentially the only drug currently available for treatment and control of schistosomiasis, a disease affecting hundreds of millions worldwide. Though highly effective overall, PZQ has limitations, most notably its significant lack of activity against immature schistosomes. Furthermore, the availability of only a single drug for a disease of this magnitude makes reports of PZQ-resistant...

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PMID: 25516841
DOI: 10.1016/j.ijpddr.2014.09.007

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