Article
Uncovering Biological Application of Brazilian Green Propolis: A Phenotypic Screening against Schistosoma mansoni.
Chemistry & biodiversity - 1 Sept 2020
A de L Paula Lucas, Santos Mario F C, Pagotti Mariana C, Faleiros Renata, Ramos Henrique P, Veneziani Rodrigo C S, Bastos Jairo K, Caffrey Conor R, Ambrosio Sérgio R, Magalhães Lizandra G
Abstract excerpt
The chemotherapy of schistosomiasis remains centered in the use of praziquantel, however, there has been growing resistant parasites to this drug. Thus, the aim of this work was to evaluate in vitro schistosomicidal activity of the hexanes/dichloromethane 1 : 1 extract of Brazilian green propolis (Pex), as well as its major isolated compounds artepillin C, caffeic acid, coumaric acid and drupanin against...
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