Article
Roles of human apolipoprotein E in the infectivity and replication of hepatitis C virus genotype 2a.
Journal of microbiology (Seoul, Korea) - 1 Jun 2016
Jung Bo-Kyoung, Kim Hye-Ran, Park Gyu-Nam, Luo Guangxiang, Chang Kyung-Soo
Abstract excerpt
Hepatitis C virus (HCV) infection is associated with lipoproteins, and apolipoprotein E (apoE) plays an essential role in infectious HCV particles. Although the role of apoE in HCV infection is well known, its role in the replication of HCV remains unclear. The aims of this study were to determine the role of apoE in the RNA replication of major HCV genotypes 1b and 2a, and to determine whether this role is...
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