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Article

Hepatitis C virus genotypes 1-3 infections regulate lipogenic signaling and suppress cholesterol biosynthesis in hepatocytes.

Journal of the Formosan Medical Association = Taiwan yi zhi - 1 Sept 2020

Hsu Ching-Sheng, Liu Wei-Liang, Li Qisheng, Lowey Brianna, Hertz Laura, Chao You-Chen, Liang T Jake, Chen Ding-Shinn, Kao Jia-Horng

Abstract excerpt

BACKGROUND: Patients with different hepatitis C virus (HCV) genotype infections are associated with varying metabolic disorders. Although alteration of lipid metabolism has been confirmed as a virus-induced metabolic derangement in chronic hepatitis C patients, the impact of various HCV genotypes on hepatic cholesterol metabolism remains elusive. In this study, we thus investigated the HCV genotype-specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32284164
DOI: 10.1016/j.jfma.2020.03.018
PMCID: PMC11492201

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