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Article

Neglected but Important Role of Apolipoprotein E Exchange in Hepatitis C Virus Infection

18 Aug 2016

Abstract excerpt

Hepatitis C virus (HCV) is a major cause of chronic liver disease, infecting approximately 170 million people worldwide. HCV assembly is tightly associated with the lipoprotein pathway. Exchangeable apolipoprotein E (apoE) is incorporated on infectious HCV virions and is important for infectious HCV virion morphogenesis and entry. Moreover, the virion apoE level is positively correlated with its ability to escape...

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PMID: 27535051
DOI: 10.1128/jvi.01353-16

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