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Article

A single endoplasmic reticulum aminopeptidase-1 protein allotype is a strong risk factor for Behçet's disease in HLA-B*51 carriers.

Annals of the rheumatic diseases - 1 Dec 2016

Takeuchi Masaki, Ombrello Michael J, Kirino Yohei, Erer Burak, Tugal-Tutkun Ilknur, Seyahi Emire, Özyazgan Yilmaz, Watts Norman R, Gül Ahmet, Kastner Daniel L, Remmers Elaine F

Abstract excerpt

INTRODUCTION: Endoplasmic reticulum aminopeptidase-1 (ERAP1) protein is highly polymorphic with numerous missense amino acid variants. We sought to determine the naturally occurring ERAP1 protein allotypes and their contribution to Behçet's disease. METHODS: Genotypes of all reported missense ERAP1 gene variants with 1000 Genomes Project EUR superpopulation frequency >1% were determined in 1900 Behçet's disease...

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Share to Aminopeptidases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27217550
DOI: 10.1136/annrheumdis-2015-209059
PMCID: PMC5106293

Genes

ERAP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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