Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Germline miRNA DNA variants and the risk of colorectal cancer by subtype.

Genes, chromosomes & cancer - 1 Mar 2017

Lindor Noralane M, Larson Melissa C, DeRycke Melissa S, McDonnell Shannon K, Baheti Saurabh, Fogarty Zachary C, Win Aung Ko, Potter John D, Buchanan Daniel D, Clendenning Mark, Newcomb Polly A, Casey Graham, Gallinger Steven, Le Marchand Loïc, Hopper John L, Jenkins Mark A, Goode Ellen L, Thibodeau Stephen N

Abstract excerpt

MicroRNAs (miRNAs) regulate up to one-third of all protein-coding genes including genes relevant to cancer. Variants within miRNAs have been reported to be associated with prognosis, survival, response to chemotherapy across cancer types, in vitro parameters of cell growth, and altered risks for development of cancer. Five miRNA variants have been reported to be associated with risk for development of colorectal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Follow-Up Studies

Share to Germ-Line Mutation

Share to MicroRNAs

Share to Neoplasm Staging

Share to Prognosis

Source

Open in PubMed Open full text

Identifiers

PMID: 27636879
DOI: 10.1002/gcc.22420
PMCID: PMC5245119

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Germline miRNA DNA variants and the risk of colorectal cancer by subtype.PMID 27636879Read ↗

Role of miRNA gene variants in the susceptibility and pharmacogenetics of colorectal cancer.Semantic proximity Read ↗

Molecular phenotypes of colorectal cancer and potential clinical applicationsSemantic proximity Read ↗

Polymorphisms in Non-coding RNA Genes and Their Targets Sites as Risk Factors of Sporadic Colorectal Cancer.Semantic proximity Read ↗

Association of DNA repair gene polymorphisms with colorectal cancer risk and treatment outcomes.Semantic proximity Read ↗

mirSNPs as Potential Colorectal Cancer Biomarkers: A Systematic ReviewSemantic proximity Read ↗

Mismatch Repair and Colon Cancer: Mechanisms and Therapies Explored.Semantic proximity Read ↗

MicroRNAs and colon and rectal cancer: differential expression by tumor location and subtype.Semantic proximity Read ↗

Colorectal cancer intrinsic subtypes predict chemotherapy benefit, deficient mismatch repair and epithelial‐to‐mesenchymal transitionSemantic proximity Read ↗

Colorectal cancer in patients of advanced age is associated with increased incidence of BRAF p.V600E mutation and mismatch repair deficiencySemantic proximity Read ↗

Heterogeneity of mismatch repair defect in colorectal cancer and its implications in clinical practiceSemantic proximity Read ↗

Systemic circulating microRNA landscape in Lynch syndromeSemantic proximity Read ↗

Investigation of colorectal cancer in accordance with consensus molecular subtype classificationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.