Article
Exploring phenotype patterns of breast cancer within somatic mutations: a modicum in the intrinsic code.
Briefings in bioinformatics - 1 Jul 2017
Yotsukura Sohiya, Karasuyama Masayuki, Takigawa Ichigaku, Mamitsuka Hiroshi
Abstract excerpt
Triple-negative (TN) breast cancer (BC) patients have limited treatment options and poor prognosis even after extant treatments and standard chemotherapeutic regimens. Linking TN patients to clinically known phenotypes with appropriate treatments is vital. Location-specific sequence variants are expected to be useful for this purpose by identifying subgroups within a disease population. Single gene mutational...
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