Article
Genome-Wide Association Study of Absolute QRS Voltage Identifies Common Variants of TBX3 as Genetic Determinants of Left Ventricular Mass in a Healthy Japanese Population.
PloS one - 1 Jan 2016
Sano Motoaki, Kamitsuji Shigeo, Kamatani Naoyuki, Tabara Yasuharu, Kawaguchi Takahisa, Matsuda Fumihiko, Yamagishi Hiroyuki, Fukuda Keiichi
Abstract excerpt
Left ventricular hypertrophy (LVH) represents a common final pathway leading to heart failure. We have searched for genetic determinants of left ventricular (LV) mass using values for absolute electrocardiographic QRS voltage in a healthy Japanese population. After adjusting for covariates, the corrected S and R wave voltages in leads V1 and V5 from 2,994 healthy volunteers in the Japan Pharmacogenomics Data...
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