SNP rs3825214 in TBX5 is associated with lone atrial fibrillation in Chinese Han population.

doi:10.1371/journal.pone.0064966

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Article

SNP rs3825214 in TBX5 is associated with lone atrial fibrillation in Chinese Han population.

PloS one - 1 Jan 2013

Zang Xiaobiao, Zhang Shulong, Xia Yunlong, Li Sisi, Fu Fenfen, Li Xiuchun, Wang Fan, Zhang Rongfeng, Tian Xiaochen, Gao Lianjun, Zhang Jiaying, Yang Yanzong, Tu Xin, Wang Qing

Abstract excerpt

BACKGROUND: A prolonged PR interval is a sign of increased risk of cardiac arrhythmia. Recent genome-wide association studies found that the single-nucleotide polymorphism (SNP) rs3825214 in T-box 5 (TBX5) was positively associated with PR interval, QRS duration, QT interval, and common arrhythmia disorders such as atrial fibrillation (AF) and advanced atrioventricular block. However, other independent...

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PMID: 23717681
DOI: 10.1371/journal.pone.0064966
PMCID: PMC3663751

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TBX5

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