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Article

TBX5 genetic variants and SCD-CAD susceptibility: insights from Chinese Han cohorts.

PeerJ - 1 Jan 2024

Rui Yukun, Zhou Ju, Zhen Xiaoyuan, Zhang Jianhua, Liu Shiquan, Gao Yuzhen

Abstract excerpt

Background: The prevention and prediction of sudden cardiac death (SCD) present persistent challenges, prompting exploration into common genetic variations for potential insights. T-box 5 (TBX5), a critical cardiac transcription factor, plays a pivotal role in cardiovascular development and function. This study systematically examined variants within the 500-bp region downstream of the TBX5 gene, focusing on...

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Identifiers

PMID: 38525280
DOI: 10.7717/peerj.17139
PMCID: PMC10959103

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