Article
Genome-wide association study of electrocardiographic parameters identifies a new association for PR interval and confirms previously reported associations.
Human molecular genetics - 15 Dec 2014
Sano Motoaki, Kamitsuji Shigeo, Kamatani Naoyuki, Hong Kyung-Won, Han Bok-Ghee, Kim Yeonjung, Kim Jong Wook, Aizawa Yoshiyasu, Fukuda Keiichi
Abstract excerpt
Previous reports have described several associations of PR, QRS, QT and heart rate with genomic variations by genome-wide association studies (GWASs). In the present study, we examined the association of ∼2.5 million SNPs from 2994 Japanese healthy volunteers obtained from the JPDSC database with electrocardiographic parameters. We confirmed associations of PR interval, QRS duration and QT interval in individuals...
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