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Article

Association of T-box gene polymorphisms with the risk of Wolff-Parkinson-White syndrome in a Han Chinese population.

Medicine - 12 Aug 2022

Han Bing, Wang Yongxiang, Zhao Jing, Lan Qingsu, Zhang Jin, Meng Xiaoxue, Jin Jianjian, Bai Ming, Zhang Zheng

Abstract excerpt

Abnormal development of the atrioventricular ring can lead to the formation of a bypass pathway and the occurrence of Wolff-Parkinson-White (WPW) syndrome. The genetic mechanism underlying the sporadic form of WPW syndrome remains unclear. Existing evidence suggests that both T-box transcription factor 3 (TBX3) and T-box transcription factor 2 (TBX2) genes participate in regulating annulus fibrosus formation and...

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PMID: 35960099
DOI: 10.1097/MD.0000000000030046
PMCID: PMC9371508

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