Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice.

Scientific reports - 19 May 2016

Ricard Clément, Tchoghandjian Aurélie, Luche Hervé, Grenot Pierre, Figarella-Branger Dominique, Rougon Geneviève, Malissen Marie, Debarbieux Franck

Abstract excerpt

Inflammatory cells, an integral component of tumor evolution, are present in Glioblastomas multiforme (GBM). To address the cellular basis and dynamics of the inflammatory microenvironment in GBM, we established an orthotopic syngenic model by grafting GL261-DsRed cells in immunocompetent transgenic LysM-EGFP//CD11c-EYFP reporter mice. We combined dynamic spectral two-photon imaging with multiparametric cytometry...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms
Share to Dendritic Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glioblastoma

Share to Luminescent Proteins

Share to Microglia

Share to Monocytes

Share to Multimodal Imaging

Share to Neoplasm Transplantation

Source

Open in PubMed Open full text

Identifiers

PMID: 27193333
DOI: 10.1038/srep26381
PMCID: PMC4872227

Genes

XCR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic dynamics of microglial and monocyte-derived cells in glioblastoma-bearing mice.PMID 27193333Read ↗

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenografts.Semantic proximity Read ↗

Glioblastoma-instructed microglia transition to heterogeneous phenotypic states with phagocytic and dendritic cell-like features in patient tumors and patient-derived orthotopic xenograftsSemantic proximity Read ↗

Dynamics of glioma-associated microglia and macrophages reveals their divergent roles in the immune response of brainSemantic proximity Read ↗

Disease-associated microglia adopt stage-specific phenotypes that regulate T cell fate and immunity in glioma.Semantic proximity Read ↗

Interplay of Glioblastoma Cells with Microglia Shapes Invasive Phenotypes during Long-distance Invasion.Semantic proximity Read ↗

A Microglial Subset at the Tumor-Stroma Interface of GliomaSemantic proximity Read ↗

Single-cell image analysis reveals a protective role for microglia in glioblastomaSemantic proximity Read ↗

SMAC mimetic drives microglia phenotype and glioblastoma immune microenvironment.Semantic proximity Read ↗

The Eclectic Nature of Glioma-Infiltrating Macrophages and Microglia.Semantic proximity Read ↗

Glioma-Associated Microglia/Macrophages Display an Expression Profile Different from M1 and M2 Polarization and Highly Express Gpnmb and Spp1Semantic proximity Read ↗

In Search for Reliable Markers of Glioma-Induced Polarization of MicrogliaSemantic proximity Read ↗

Chemoradiation-Altered Micromilieu of Glioblastoma Cells Particularly Impacts M1-Like Macrophage ActivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.