Article
The Eclectic Nature of Glioma-Infiltrating Macrophages and Microglia.
International journal of molecular sciences - 13 Dec 2021
Arrieta Víctor A, Najem Hinda, Petrosyan Edgar, Lee-Chang Catalina, Chen Peiwen, Sonabend Adam M, Heimberger Amy B
Abstract excerpt
Glioblastomas (GBMs) are complex ecosystems composed of highly multifaceted tumor and myeloid cells capable of responding to different environmental pressures, including therapies. Recent studies have uncovered the diverse phenotypical identities of brain-populating myeloid cells. Differences in the immune proportions and phenotypes within tumors seem to be dictated by molecular features of glioma cells....
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