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Article

The prognostic role of RANK SNP rs34945627 in breast cancer patients with bone metastases.

Oncotarget - 5 Jul 2016

Ferreira Arlindo, Alho Irina, Vendrell Inês, Melo Marta, Brás Raquel, Costa Ana Lúcia, Sousa Ana Rita, Mansinho André, Abreu Catarina, Pulido Catarina, Macedo Daniela, Pacheco Teresa, Correia Lurdes, Costa Luis, Casimiro Sandra

Abstract excerpt

Receptor activator of NF-kB (RANK) pathway regulates bone remodeling and is involved in breast cancer (BC) progression. Genetic polymorphisms affecting RANK-ligand (RANKL) and osteoprotegerin (OPG) have been previously associated with BC risk and bone metastasis (BM)-free survival, respectively. In this study we conducted a retrospective analysis of the association of five missense RANK SNPs with clinical...

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Identifiers

PMID: 27191503
DOI: 10.18632/oncotarget.9356
PMCID: PMC5173066

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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