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Article

Genetic polymorphism of the OPG gene associated with breast cancer.

BMC cancer - 31 Jan 2013

Ney Jasmin Teresa, Juhasz-Boess Ingolf, Gruenhage Frank, Graeber Stefan, Bohle Rainer Maria, Pfreundschuh Michael, Solomayer Erich Franz, Assmann Gunter

Abstract excerpt

BACKGROUND: The receptor activator of NF-κB (RANK), its ligand (RANKL) and osteoprotegerin (OPG) have been reported to play a role in the pathophysiological bone turnover and in the pathogenesis of breast cancer. Based on this we investigated the role of single nucleotide polymorphisms (SNPs) within RANK, RANKL and OPG and their possible association to breast cancer risk. METHODS: Genomic DNA was obtained from...

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Identifiers

PMID: 23369128
DOI: 10.1186/1471-2407-13-40
PMCID: PMC3563620

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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