Article
The association between RANKL and Osteoprotegerin gene polymorphisms with breast cancer.
Molecular and cellular biochemistry - 1 May 2015
Omar Heba S, Shaker Olfat G, Nassar Yasser H, Marzouk Samar A, ElMarzouky Mohamed S
Abstract excerpt
Breast cancer is the most common cause of cancer death among women (522,000 deaths in 2012). Imbalance between RANKL and OPG is observed in many cancers, including breast cancer. Consequently, SNPs in the genes of RANKL and OPG may be involved in breast cancer development. This study included 276 subjects. Group I (n = 100) healthy females as a control group, group II (n = 96) breast cancer patients without bone...
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