Article
Identification of novel RANK polymorphisms and their putative association with low BMD among postmenopausal women.
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA - 1 Mar 2007
Koh J-M, Park B L, Kim D J, Kim G S, Cheong H S, Kim T-H, Hong J-M, Shin H-I, Park E K, Kim S-Y, Shin H D
Abstract excerpt
INTRODUCTION: Bone mineral density (BMD) is the major factor for determining bone strength, which is closely correlated to osteoporotic fracture risk and is largely determined by multiple genetic factors. The RANK (TNFRSF11A), receptor for RANKL, is a member of the tumor necrosis factor receptor (TNFR) superfamily and plays a central role in osteoclast development. METHODS: In order to investigate the effects of...
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