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Article

Differential effects of NOX4 and NOX1 on immune cell-mediated inflammation in the aortic sinus of diabetic ApoE-/- mice.

Clinical science (London, England : 1979) - 1 Aug 2016

Di Marco Elyse, Gray Stephen P, Chew Phyllis, Kennedy Kit, Cooper Mark E, Schmidt Harald H H W, Jandeleit-Dahm Karin A M

Abstract excerpt

Oxidative stress and inflammation are central mediators of atherosclerosis particularly in the context of diabetes. The potential interactions between the major producers of vascular reactive oxygen species (ROS), NADPH oxidase (NOX) enzymes and immune-inflammatory processes remain to be fully elucidated. In the present study we investigated the roles of the NADPH oxidase subunit isoforms, NOX4 and NOX1, in...

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Share to Atherosclerosis
Share to Chemotaxis, Leukocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Experimental

Share to Immunity, Cellular

Share to Inflammation Mediators

Share to NADH, NADPH Oxidoreductases

Share to NADPH Oxidases

Share to Plaque, Atherosclerotic

Source

Identifiers

PMID: 27190136
DOI: 10.1042/CS20160249

Genes

NOX4
NOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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