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Article

Diabetic atherosclerosis in APOE*4 mice: synergy between lipoprotein metabolism and vascular inflammation.

Journal of lipid research - 1 Feb 2013

Johnson Lance A, Kim Hyung-Suk, Knudson Melissa J, Nipp C Taylor, Yi Xianwen, Maeda Nobuyo

Abstract excerpt

Diabetes is a major risk factor for cardiovascular disease. To examine how diabetes interacts with a mildly compromised lipid metabolism, we introduced the diabetogenic Ins2(C96Y/+) (Akita) mutation into mice expressing human apoE4 (E4) combined with either an overexpressing human LDL receptor ge...

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Share to Apolipoprotein E4
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23204275
DOI: 10.1194/jlr.M031435
PMCID: PMC3588868

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23204275-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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