Article
High throughput analysis of MHC class I and class II diversity of Zambian indigenous cattle populations.
HLA - 1 May 2023
Silwamba Isaac, Vasoya Deepali, Simuunza Martin, Tzelos Thomas, Nalubamba King S, Simulundu Edgar, Vrettou Christina, Mainda Geoffrey, Watson Mick, Muma John Bwalya, Connelley Timothy
Abstract excerpt
The classical MHC class I and class II molecules play key roles in determining the antigenic-specificity of CD8+ and CD4+ T-cell responses-as such characterisation of the repertoire of MHCI and MHCII allelic diversity is fundamental to our ability to understand, and potentially, exploit how genetic diversity influences the outcome of immune responses. Cattle remain one of the most economically livestock species,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.