Article
High throughput analysis of MHC-I and MHC-DR diversity of Brazilian cattle populations.
HLA - 1 Aug 2021
Vasoya Deepali, Oliveira Priscila Silva, Muriel Laura Agundez, Tzelos Thomas, Vrettou Christina, Morrison W Ivan, de Miranda Santos Isabel Kinney Ferreira, Connelley Timothy
Abstract excerpt
The major histocompatibility complex (MHC) contains many genes that play key roles in initiating and regulating immune responses. This includes the polymorphic MHCI and MHCII genes that present epitopes to CD8+ and CD4+ T-cells, respectively. Consequently, the characterisation of the repertoire of MHC genes is an important component of improving our understanding of the genetic variation that determines the...
Topics
- Alleles
- Animals
- Brazil
- Cattle
- Genetic Variation
- Haplotypes
- Histocompatibility Antigens Class II
- Major Histocompatibility Complex
