Article
Kinase-targeted cancer therapies: progress, challenges and future directions
15 Feb 2018
Abstract excerpt
The human genome encodes 538 protein kinases that transfer a γ-phosphate group from ATP to serine, threonine, or tyrosine residues. Many of these kinases are associated with human cancer initiation and progression. The recent development of small-molecule kinase inhibitors for the treatment of diverse types of cancer has proven successful in clinical therapy. Significantly, protein kinases are the second most...
Topics
Join the communities discussing this publication.