Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challenges

15 Feb 2018

Abstract excerpt

Breast cancer is a multifactorial disease and driven by aberrant regulation of cell signaling pathways due to the acquisition of genetic and epigenetic changes. An array of growth factors and their receptors is involved in cancer development and metastasis. Receptor Tyrosine Kinases (RTKs) constitute a class of receptors that play important role in cancer progression. RTKs are cell surface receptors with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokine Signaling Pathways and Interactions
Share to HER2/EGFR in Cancer Research
Share to PI3K/AKT/mTOR signaling in cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29455658
DOI: 10.1186/s12943-018-0797-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Receptor tyrosine kinases (RTKs) in breast cancer: signaling, therapeutic implications and challengesPMID 29455658Read ↗

Receptor tyrosine kinases: biological functions and anticancer targeted therapySemantic proximity Read ↗

Mechanisms of receptor tyrosine kinase activation in cancer.Semantic proximity Read ↗

Roles for receptor tyrosine kinases in tumor progression and implications for cancer treatment.Semantic proximity Read ↗

The Tyrosine Kinome Dictates Breast Cancer Heterogeneity and Therapeutic ResponsivenessSemantic proximity Read ↗

Current Status of Fibroblast Growth Factor Receptors Targeted Therapies in Breast CancerSemantic proximity Read ↗

Receptor tyrosine kinases: from biology to pathology.Semantic proximity Read ↗

Epidermal growth factor receptor mutations in breast Cancer: Therapeutic challenges and way forward.Semantic proximity Read ↗

Receptor Tyrosine Kinase-Targeted Cancer TherapySemantic proximity Read ↗

Molecular biology of human epidermal receptors, signaling pathways and targeted therapy against cancers: new evidences and old challengesSemantic proximity Read ↗

ErbB receptors and signaling pathways in cancer.Semantic proximity Read ↗

Transforming growth factor-β signaling in tumor initiation, progression and therapy in breast cancer: an updateSemantic proximity Read ↗

To Investigate Growth Factor Receptor Targets and Generate Cancer Targeting InhibitorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.