Article
Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population.
Nature genetics - 15 Jul 2012
Dong Jing, Hu Zhibin, Wu Chen, Guo Huan, Zhou Baosen, Lv Jiachun, Lu Daru, Chen Kexin, Shi Yongyong, Chu Minjie, Wang Cheng, Zhang Ruyang, Dai Juncheng, Jiang Yue, Cao Songyu, Qin Zhenzhen, Yu Dianke, Ma Hongxia, Jin Guangfu, Gong Jianhang, Sun Chongqi, Zhao Xueying, Yin Zhihua, Yang Lei, Li Zhiqiang, Deng Qifei, Wang Jiucun, Wu Wei, Zheng Hong, Zhou Guoquan, Chen Hongyan, Guan Peng, Peng Zhihang, Chen Yijiang, Shu Yongqian, Xu Lin, Liu Xiangyang, Liu Li, Xu Pin, Han Baohui, Bai Chunxue, Zhao Yuxia, Zhang Haibo, Yan Ying, Amos Christopher I, Chen Feng, Tan Wen, Jin Li, Wu Tangchun, Lin Dongxin, Shen Hongbing
Abstract excerpt
To find additional susceptibility loci for lung cancer, we tested promising associations from our previous genome-wide association study (GWAS) of lung cancer in the Chinese population in an extended validation sample size of 7,436 individuals with lung cancer (cases) and 7,483 controls. We found genome-wide significant (P < 5.0 × 10(-8)) evidence for three additional lung cancer susceptibility loci at 10p14...
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