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[Association between CYP2C9 and VKORC1 genetic polymorphism and warfarin dose requirements].

Zhonghua xin xue guan bing za zhi - 1 Feb 2008

Yang Jian, Miao Li-yan, Huang Chen-rong, Shen Zhen-ya, Jiang Wen-ping

Abstract excerpt

OBJECTIVE: To assess the contribution of vitamin K epoxide reductase complex 1 (VKORC1) and cytochrome P450 2C9 (CYP2C9) genotype, age, body size, height, and weight to warfarin dose requirement. METHODS: Blood samples were collected from 191 patients receiving warfarin therapy. Patients's age, gender, height, and weight were registered. PCR-RFLP method was used for the detection of VKORC1-1639G > A and CYP2C9...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19099951

Genes

VKORC1

Provenance

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