Article
Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans.
PloS one - 1 Jan 2016
Yang Su, Xu Hong, Wang Jiali, Liu Chengzhi, Lu Huizhi, Liu Mengjia, Zhao Ye, Tian Bing, Wang Liangyan, Hua Yuejin
Abstract excerpt
The cyclic AMP receptor protein family of transcription factors regulates various metabolic pathways in bacteria, and also play roles in response to environmental changes. Here, we identify four homologs of the CRP family in Deinococcus radiodurans, one of which tolerates extremely high levels of oxidative stress and DNA-damaging reagents. Transcriptional levels of CRP were increased under hydrogen peroxide...
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