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Article

Three tandem HRDC domains have synergistic effect on the RecQ functions in Deinococcus radiodurans.

DNA repair - 4 Feb 2007

Huang Lifen, Hua Xiaoting, Lu Huiming, Gao Guanjun, Tian Bing, Shen Binghui, Hua Yuejin

Abstract excerpt

The RecQ family of DNA helicases performs essential functions in the maintenance of genomic stability in all organisms. In Deinococcus radiodurans, DR1289 is a special member of RecQ family with unique arrangement of three tandem HRDC domains in the C-terminus. A dr1289 mutant is hypersensitive to gamma-irradiation, UV, H2O2 and mitomycin C. By complementing the dr1289 mutant with various domains of Dr1289 in...

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Source

Identifiers

PMID: 17085080
DOI: 10.1016/j.dnarep.2006.09.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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