Expression and mutational analysis of DinB-like protein DR0053 in Deinococcus radiodurans.

doi:10.1371/journal.pone.0118275

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Article

Expression and mutational analysis of DinB-like protein DR0053 in Deinococcus radiodurans.

PloS one - 1 Jan 2015

Appukuttan Deepti, Seo Ho Seong, Jeong Sunwook, Im Sunghun, Joe Minho, Song Dusup, Choi Jungjoon, Lim Sangyong

Abstract excerpt

In order to understand the mechanism governing radiation resistance in Deinococcus radiodurans, current efforts are aimed at identifying potential candidates from a large repertoire of unique Deinococcal genes and protein families. DR0053 belongs to the DinB/YfiT protein family, which is an over-represented protein family in D. radiodurans. We observed that dr0053 transcript levels were highly induced in response...

Topics

Bacterial Proteins
DNA Damage
DNA Mutational Analysis
Deinococcus
Gamma Rays
Gene Expression Regulation, Bacterial
Hydrogen Peroxide
Mitomycin
Mutation
Promoter Regions, Genetic
Protein-Tyrosine Kinases
Signal Transduction
Transcription, Genetic

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Identifiers

PMID: 25706748
DOI: 10.1371/journal.pone.0118275
PMCID: PMC4338110

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