Article
DR1440 is a potential iron efflux protein involved in maintenance of iron homeostasis and resistance of Deinococcus radiodurans to oxidative stress.
PloS one - 1 Jan 2018
Dai Shang, Jin Ye, Li Tao, Weng Yulan, Xu Xiaolin, Zhang Genlin, Li Jiulong, Pang Renjiang, Tian Bing, Hua Yuejin
Abstract excerpt
Iron acquisition by bacteria is well studied, but iron export from bacteria is less understood. Herein, we identified dr1440 with a P-type ATPase motif as a potential exporter of iron from Deinococcus radiodurans, a bacterium known for its extreme resistance to radiation and oxidants. The DR1440 was located in cell membrane as demonstrated by fluorescence labelling analysis. Mutation of dr1440 resulted in...
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