Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP receptor protein (CRP).

PloS one - 1 Jan 2012

Basak Souvik, Jiang Rongrong

Abstract excerpt

Oxidative damage to microbial hosts often occurs under stressful conditions during bioprocessing. Classical strain engineering approaches are usually both time-consuming and labor intensive. Here, we aim to improve E. coli performance under oxidative stress via engineering its global regulator cAMP receptor protein (CRP), which can directly or indirectly regulate redox-sensing regulators SoxR and OxyR, and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptation, Physiological
Share to Cyclic AMP Receptor Protein
Share to Escherichia coli Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, Bacterial

Share to Oligonucleotide Array Sequence Analysis

Share to Oxidative Stress

Share to Reactive Oxygen Species

Share to Real-Time Polymerase Chain Reaction

Source

Open in PubMed Open full text

Identifiers

PMID: 23251448
DOI: 10.1371/journal.pone.0051179
PMCID: PMC3522674

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Enhancing E. coli tolerance towards oxidative stress via engineering its global regulator cAMP receptor protein (CRP).PMID 23251448Read ↗

Improving ethanol tolerance of Escherichia coli by rewiring its global regulator cAMP receptor protein (CRP).Semantic proximity Read ↗

AsrR Is an Oxidative Stress Sensing Regulator Modulating Enterococcus faecium Opportunistic Traits, Antimicrobial Resistance, and PathogenicitySemantic proximity Read ↗

Improving acetate tolerance of Escherichia coli by rewiring its global regulator cAMP receptor protein (CRP).Semantic proximity Read ↗

Laboratory-evolved mutants of an exogenous global regulator, IrrE from Deinococcus radiodurans, enhance stress tolerances of Escherichia coli.Semantic proximity Read ↗

Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans.Semantic proximity Read ↗

OxyR Is a Convergent Target for Mutations Acquired during Adaptation to Oxidative Stress-Prone Metabolic States.Semantic proximity Read ↗

The YaaA protein of the Escherichia coli OxyR regulon lessens hydrogen peroxide toxicity by diminishing the amount of intracellular unincorporated iron.Semantic proximity Read ↗

Regulation of Oxidative Stress Response by CosR, an Essential Response Regulator in Campylobacter jejuniSemantic proximity Read ↗

Experimental evolution reveals the genetic basis and systems biology of superoxide stress toleranceSemantic proximity Read ↗

Participation of stress-inducible systems and enzymes involved in BER and NER in the protection of Escherichia coli against cumene hydroperoxide.Semantic proximity Read ↗

Evidence for up and down regulation of 450 genes by rpoB12 (rif) mutation and their implications in complexity of transcription modulation in Escherichia coli.Semantic proximity Read ↗

Improvement of isopropanol tolerance of Escherichia coli using adaptive laboratory evolution and omics technologies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.