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Article

Type 3 muscarinic receptors contribute to intestinal mucosal homeostasis and clearance of Nippostrongylus brasiliensis through induction of TH2 cytokines.

American journal of physiology. Gastrointestinal and liver physiology - 1 Jul 2016

McLean Leon P, Smith Allen, Cheung Lumei, Urban Joseph F, Sun Rex, Grinchuk Viktoriya, Desai Neemesh, Zhao Aiping, Raufman Jean-Pierre, Shea-Donohue Terez

Abstract excerpt

Despite increased appreciation for the role of nicotinic receptors in the modulation of and response to inflammation, the contribution of muscarinic receptors to mucosal homeostasis, clearance of enteric pathogens, and modulation of immune cell function remains relatively undefined. Uninfected and Nippostrongylus brasiliensis-infected wild-type and type 3 muscarinic receptor (M3R)-deficient (Chrm3(-/-)) mice were...

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Identifiers

PMID: 27173511
DOI: 10.1152/ajpgi.00461.2014
PMCID: PMC4967171

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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