Article

Enteric pathogens induce tissue tolerance and prevent neuronal loss from subsequent infections

2021-04-11

Abstract excerpt

The enteric nervous system (ENS) controls several intestinal functions including motility and nutrient handling, which can be disrupted by infection-induced neuropathies or neuronal cell death. We investigated possible tolerance mechanisms preventing neuronal loss and disruption in gut motility after pathogen exposure. We found that following enteric infections, muscularis macrophages (MMs) acquire a tissue-protec...

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Literature Corpus work: 17bcafd6-4f54-5a7c-8f79-413954520fa5
DOI: 10.1101/2021.04.09.439221

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