Article
Relationship between APOE Genotype and Structural MRI Measures throughout Adulthood in the Study of Health in Pomerania Population-Based Cohort.
AJNR. American journal of neuroradiology - 1 Sept 2016
Habes M, Toledo J B, Resnick S M, Doshi J, Van der Auwera S, Erus G, Janowitz D, Hegenscheid K, Homuth G, Völzke H, Hoffmann W, Grabe H J, Davatzikos C
Abstract excerpt
BACKGROUND AND PURPOSE: The presence of the apolipoprotein E ε4 allele is the strongest sporadic Alzheimer disease genetic risk factor. We hypothesized that apolipoprotein E ε4 carriers and noncarriers may already differ in imaging patterns in midlife. We therefore sought to identify the effect of apolipoprotein E genotype on brain atrophy across almost the entire adult age span by using advanced MR imaging-based...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.