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Article

Functional mapping of the Candida albicans Efg1 regulator.

Eukaryotic cell - 1 May 2008

Noffz Christine S, Liedschulte Vanessa, Lengeler Klaus, Ernst Joachim F

Abstract excerpt

Efg1p is a key transcriptional regulator in Candida albicans which controls various aspects of morphogenesis and metabolism in this organism. Efg1p contains a central basic helix-loop-helix (bHLH) domain, flanked by sequences highly conserved in fungal APSES proteins, as well as polyglutamine stretches at the N- and C-terminal ends. A systematic deletion approach to specify functional domains of Efg1p revealed...

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Share to Candida albicans
Share to Consensus Sequence
Share to Electrophoretic Mobility Shift Assay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Fungal

Share to Genes, Regulator

Share to Helix-Loop-Helix Motifs

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Identifiers

PMID: 18375615
DOI: 10.1128/EC.00033-08
PMCID: PMC2394972

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