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Article

APSES Proteins Regulate Morphogenesis and Metabolism in<i>Candida albicans</i>

20 Apr 2004

Abstract excerpt

Fungal APSES proteins regulate morphogenetic processes, including filamentation and differentiation. The human fungal pathogen Candida albicans contains two APSES proteins: the regulator Efg1p and its homologue Efh1p, described here. Overexpression of EFG1 or EFH1 led to similar phenotypes, including pseudohypha formation and opaque-white switching. An efh1 deletion generated no phenotype under most conditions...

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PMID: 15218092
DOI: 10.1091/mbc.e03-11-0782

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