Article
Several Critical Cell Types, Tissues, and Pathways Are Implicated in Genome-Wide Association Studies for Systemic Lupus Erythematosus.
G3 (Bethesda, Md.) - 1 Jun 2016
Liu Lu, Yin Xianyong, Wen Leilei, Yang Chao, Sheng Yujun, Lin Yan, Zhu Zhengwei, Shen Changbing, Shi Yinjuan, Zheng Yajie, Yang Sen, Zhang Xuejun, Cui Yong
Abstract excerpt
We aimed to elucidate the cell types, tissues, and pathways influenced by common variants in systemic lupus erythematosus (SLE). We applied a nonparameter enrichment statistical approach, termed SNPsea, in 181 single nucleotide polymorphisms (SNPs) that have been identified to be associated with the risk of SLE through genome-wide association studies (GWAS) in Eastern Asian and Caucasian populations, to...
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