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The Identification of Significant Genes Related to Systemic Lupus Erythematosus through the Integration of the Results of a Transcriptome-Wide Association Study and an mRNA Expression Profile Analysis

2022-11-03

Abstract excerpt

<h4>Background: </h4> Systemic lupus erythematosus (SLE) is a polygenic autoimmune connective tissue disease in which heritable components play an essential role in the pathogenesis. However, the correlation between genetic variants and pathological changes in SLE is still unclear, and it is difficult to provide insights for the early diagnosis and treatment of SLE. Methods We conducted a transcriptome-wide assoc...

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Literature Corpus work: a3cefaa8-8fe2-55e4-81bf-2b684f625b5f
DOI: 10.21203/rs.3.rs-2216395/v1

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