Article
Identification of cell types, tissues and pathways affected by risk loci in psoriasis.
Molecular genetics and genomics : MGG - 1 Apr 2016
Lin Yan, Zhao Pan, Shen Changbing, Shen Songke, Zheng Xiaodong, Zuo Xianbo, Yang Sen, Zhang Xuejun, Yin Xianyong
Abstract excerpt
Many common variants have been found associated with the risk of psoriasis, but the underlying mechanism is still largely unknown, mostly owing to the difficulty in dissecting the mechanism of each variant using representative cell type and tissue in biological experiments. We applied an integrative method SNPsea which has been developed by investigators in Broad, to identify the most relevant cell types,...
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