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Article

BMI1 in the heart: Novel functions beyond tumorigenesis

1 Jan 2021

Abstract excerpt

The BMI1 protein, a member of the PRC1 family, is a well recognised transcriptional suppressor and has the capability of maintaining the self-renewal and proliferation of tissue-specific stem cells. Numerous studies have established that BMI1 is highly expressed in a variety of malignant cancers and serves as a key regulator in the tumorigenesis process. However, our understanding of BMI1 in terminally...

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PMID: 33421944
DOI: 10.1016/j.ebiom.2020.103193

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