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Article

Integrated Genomics for Pinpointing Survival Loci within Arm-Level Somatic Copy Number Alterations.

Cancer cell - 9 May 2016

Roy David M, Walsh Logan A, Desrichard Alexis, Huse Jason T, Wu Wei, Gao JianJiong, Bose Promita, Lee William, Chan Timothy A

Abstract excerpt

The identification of driver loci underlying arm-level somatic copy number alterations (SCNAs) in cancer has remained challenging and incomplete. Here, we assess the relative impact and present a detailed landscape of arm-level SCNAs in 10,985 patient samples across 33 cancer types from The Cancer Genome Atlas (TCGA). Furthermore, using chromosome 9p loss in lower grade glioma (LGG) as a model, we employ a unique...

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Source

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Identifiers

PMID: 27165745
DOI: 10.1016/j.ccell.2016.03.025
PMCID: PMC4864611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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