Article
High-resolution global genomic survey of 178 gliomas reveals novel regions of copy number alteration and allelic imbalances.
Cancer research - 1 Oct 2006
Kotliarov Yuri, Steed Mary Ellen, Christopher Neil, Walling Jennifer, Su Qin, Center Angela, Heiss John, Rosenblum Mark, Mikkelsen Tom, Zenklusen Jean C, Fine Howard A
Abstract excerpt
Primary brain tumors are the fourth leading cause of cancer mortality in adults under the age of 54 years and the leading cause of cancer mortality in children in the United States. Therapy for the most common type of primary brain tumors, gliomas, remains suboptimal. The development of new and more effective treatments will likely require a better understanding of the biology of these tumors. Here, we show that...
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