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Article

Isolation and Mechanical Measurements of Myofibrils from Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes.

Stem cell reports - 14 Jun 2016

Pioner Josè Manuel, Racca Alice W, Klaiman Jordan M, Yang Kai-Chun, Guan Xuan, Pabon Lil, Muskheli Veronica, Zaunbrecher Rebecca, Macadangdang Jesse, Jeong Mark Y, Mack David L, Childers Martin K, Kim Deok-Ho, Tesi Chiara, Poggesi Corrado, Murry Charles E, Regnier Michael

Abstract excerpt

Tension production and contractile properties are poorly characterized aspects of excitation-contraction coupling of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs). Previous approaches have been limited due to the small size and structural immaturity of early-stage hiPSC-CMs. We developed a substrate nanopatterning approach to produce hiPSC-CMs in culture with adult-like dimensions,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27161364
DOI: 10.1016/j.stemcr.2016.04.006
PMCID: PMC4911495

Genes

MYH7

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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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