Article
Modelling sarcomeric cardiomyopathies with human cardiomyocytes derived from induced pluripotent stem cells
9 Jan 2019
Abstract excerpt
Cardiomyocytes derived from human induced pluripotent stem cells (iPSCs) provide a unique opportunity to understand the pathophysiological effects of genetic cardiomyopathy mutations. In particular, these cells hold the potential to unmask the effects of mutations on contractile behaviour in vitro, providing new insights into genotype-phenotype relationships. With this goal in mind, several groups have...
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