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Longitudinal whole genome analysis of pre and post drug treatment Mycobacterium tuberculosis isolates reveals progressive steps to drug resistance.

Tuberculosis (Edinburgh, Scotland) - 1 May 2016

Datta Gargi, Nieto Luisa M, Davidson Rebecca M, Mehaffy Carolina, Pederson Caroline, Dobos Karen M, Strong Michael

Abstract excerpt

Tuberculosis (TB) is one of the leading causes of death due to an infectious disease in the world. Understanding the mechanisms of drug resistance has become pivotal in the detection and treatment of newly emerging resistant TB cases. We have analyzed three pairs of Mycobacterium tuberculosis strains pre- and post-drug treatment to identify mutations involved in the progression of resistance to the drugs...

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Identifiers

PMID: 27156618
DOI: 10.1016/j.tube.2016.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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