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Uncovering resistance pathways to first- and last-line antibiotics in Mycobacterium tuberculosis populations.

Microbial genomics - 1 May 2026

Srilohasin Prapaporn, Williams Jasmine M, Tay Aidan P, Gillieatt Brodie F, Pascoe Daniel R, Maharjan Ram P, Chaipraset Angkana, Ajawatanawong Pravech, Cain Amy K

Abstract excerpt

Tuberculosis (TB), caused by Mycobacterium tuberculosis, is one of the world's deadliest diseases, currently responsible for ~1.5 million deaths per year and rising. Recently, rifampicin-resistant M. tuberculosis was designated as a critical priority pathogen status by the World Health Organization. However, few controlled laboratory studies are available that systematically assess the molecular drivers of...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42154617
DOI: 10.1099/mgen.0.001723
PMCID: PMC13186403

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