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Article

Detection of a novel mutation in the rpoB gene in a multidrug resistant Mycobacterium tuberculosis isolate using whole genome next generation sequencing.

Journal of global antimicrobial resistance - 1 Sept 2020

Hirani Nilma, Joshi Ameeta, Anand Siddharth, Chowdhary Abhay, Ganesan Karthik, Agarwal Meenal, Phadke Nikhil

Abstract excerpt

BACKGROUND: Mycobacterium tuberculosis (Mtb) drug resistance is a global concern. Moreover, multiple drug resistant (MDR), extensively drug resistant (XDR), and totally drug resistant (TDR) Mtb cases are on the rise in developing countries like India. Most of these cases are identified only 3-6 months after initiation of treatment owing to incomplete/failed clinical response and incomplete information from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32200129
DOI: 10.1016/j.jgar.2020.03.004

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